PEPTIDE CONJUGATION AND MODIFICATION

As a leader in peptide synthesis, ProteoGenix offers a very wide range of possible modifications. Below is a non-exhaustive list of what we offer but if you don’t find the peptide modifications you are looking for, feel free to let us know; it is very likely that we are capable of producing them.

N- C- Terminal Modification

3-(p-Hydroxyphenyl) propionic Acid
(Dnp, N-Terminal)
Acetylation (Lys)
Acetylation (N-Terminal)
Alloc (N-Terminal)
AMC (C-Terminal)
Amidation (C-Terminal)
Benzyloxycarbonylation (CBZ)
Br-Ac- ((N-Terminal))
CMK/FMK (C-Terminal)
DL-Lipoic acid (N-Terminal)
Fatty acid (N-Terminal)
Formylation (N-Terminal)
Lys(Pal) (middle, C-Terminal)
Maleimide (N-Terminal)
Myristic acid (N-Terminal)
NHEt (C-Terminal)
NHisopen (C-Terminal)
NHMe (C-Terminal)
OBzl (C-Terminal)
OEt (C-Terminal)
OMe (C-Terminal)
OtBu (C-terminal)
Palmitoyl (N-Terminal)
p-Nitroanilide (pNA, C-Terminal)
Succinylation (Suc, N-Terminal)
TBzl (C-Terminal)

Quenched fluorescent peptide

Abz/ Tyr (3-NO2)
EDANS or DABCYL

Isotope label

N15 Ala
N15 Gly
N15 Val
N15 Pro
N15 Leu
N15 Phe
N15 Lys

Peptide Conjugation

KLH / OVA / BSA-Peptide (N-Terminal or Cysteine)
Horse Radish Peroxidase (HRP)
Ovalbumin
Myoglobin

Fluorescence/Dye Labeling

(Lys(Dnp)) (middle)
(Lys(Maleimide)), (middle)
3-Indolylacetic acid (N-Terminal)
5-TAMRA (N-Terminal)
Biotin (N-Terminal, Y/N Ahx)
Biotin (Lys in sequence)
Biotin (without Lys in sequence)
Dansyl (N-Terminal, Y/N Ahx)
Dansyl (Lys in sequence)
DTPA (N-Terminal)
EDBiotin (C-Terminal)
EDDnp (C-Terminal)
FITC/5-FAM (N-Terminal, Y/N Ahx)
FITC/5-FAM (Lys in sequence)
HYNIC (N-Terminal)
Lys (Pen)
Lys(TMR) (C-Terminal)
Lys(TMR) (middle)
MCA (C-Terminal conjugated to the Lys side chain)
MCA (N-Terminal)
Palmitoylation (side chain of the Cys)
Rhodamine (N-Terminal)
Rhodamine (without Lys in sequence)
TMR (N-Terminal)

Cyclic peptide

Mono Disulfide bridge
Double Disulfide bridge
Triple Disulfide bridge
Amide cyclic (Side chain, end)
Intermolecular (Side chain, end)

Phosphorylation

(pSer)
(pTyr)
(pThr)
Di-sites in sequence
Tri-sites in sequence

If you cannot find a modification in this list, please let us know. We can provide many other modifications, and it is difficult to gather all of them into a list.