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Brand: ProteoGenix

CD122 / IL2RB, C-His, recombinant protein

Host species:
Mammalian cells
Origin species:
Homo sapiens (Human)
Molecular weight:
28.32 kDa

$500.00

100ug + 500 loyalty points
Met1–Asp239 His
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CD122 / IL2RB, C-His, recombinant protein

CD122 / IL2RB, C-His, recombinant protein

Product name CD122 / IL2RB, C-His, recombinant protein
Origin species Homo sapiens (Human)
Expression system Eukaryotic expression
Molecular weight 28.32 kDa
Protein delivered with Tag? C-terminal His Tag
Purity estimated >90% as determined by SDS-PAGE
Buffer PBS, pH7.5
Delivery condition Dry Ice
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Mammalian cells
Fragment Type Met1-Asp239
Protein Accession P14784
Reference PX-P5555
Note For research use only
Molecular Constructor
Met1–Asp239 His

General information on CD122 / IL2RB, C-His, recombinant protein

CD122/IL2RB Structure

CD122, also known as Interleukin-2 Receptor Beta (IL2RB), is a type I transmembrane glycoprotein that belongs to the cytokine receptor superfamily. It is composed of an extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain is composed of three immunoglobulin-like domains, while the intracellular domain consists of two tyrosine-based activation motifs.

CD122/IL2RB Activity

CD122 is a receptor for Interleukin-2 (IL-2), a cytokine that plays an important role in the regulation of the immune response. The binding of IL-2 to CD122 triggers a series of intracellular signaling pathways, leading to the activation of various downstream molecules such as Janus kinases (JAKs) and signal transducers and activators of transcription (STATs).

CD122/IL2RB Application

CD122 plays an important role in the regulation of the immune response, and its expression has been associated with various immune disorders, such as autoimmune diseases, allergies, and cancer. In addition, CD122 has been studied as a potential target for therapeutic intervention in these diseases.

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