Recombinant Human KRT20, N-His

Reference: YHE16101
Product nameRecombinant Human KRT20, N-His
Uniprot IDP35900
Origin speciesHomo sapiens (Human)
Expression systemProcaryotic expression
Protein delivered with Tag?N-Terminal His Tag
Buffer0.01M PBS, pH 7.4.
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandAntibodySystem
Host speciesEscherichia coli (E.coli)
Aliases /SynonymsProtein IT, Keratin-20, Cytokeratin-20, KRT20, K20, CK-20, Keratin, type I cytoskeletal 20
ReferenceYHE16101
NoteFor research use only

Description of Recombinant Human KRT20, N-His

Introduction

Recombinant Human KRT20, N-His is a type of protein that has been genetically engineered in a lab setting. This protein is commonly used in scientific research and has potential applications in the development of new drugs. In this article, we will explore the structure, activity, and potential applications of Recombinant Human KRT20, N-His.

Structure of Recombinant Human KRT20, N-His

Recombinant Human KRT20, N-His is a protein that is made up of 463 amino acids. It belongs to the keratin family of proteins, which are known for their structural role in maintaining the integrity of cells and tissues. The structure of this protein is characterized by a central alpha-helical rod domain, flanked by non-helical head and tail domains. The protein also contains several cysteine residues, which are important for maintaining its structural stability.

Activity of this protein

The main activity of Recombinant Human KRT20, N-His is to provide structural support to cells and tissues. This protein is primarily found in epithelial cells, which line the surfaces of organs and body cavities. It is a major component of the cytoskeleton, which helps to maintain the shape and integrity of cells. In addition, Recombinant Human KRT20, N-His is also involved in cell signaling and cell adhesion processes.

Role in Drug Targeting

Due to its involvement in cell signaling and adhesion, Recombinant Human KRT20, N-His has been identified as a potential drug target. Research has shown that this protein is overexpressed in certain types of cancer, such as colorectal and gastric cancer. This makes it a promising target for the development of new cancer treatments. By targeting Recombinant Human KRT20, N-His, it may be possible to disrupt the signaling pathways and inhibit the growth of cancer cells.

Application in Drug Development

Recombinant Human KRT20, N-His is also being studied for its potential applications in drug development. One area of interest is its role in drug delivery. Researchers are exploring the possibility of using this protein as a carrier molecule for targeted drug delivery to cancer cells. This could potentially improve the efficacy and reduce the side effects of cancer treatments.

In addition, Recombinant Human KRT20, N-His is also being investigated for its potential role in regenerative medicine. As a structural protein, it plays a crucial role in tissue repair and regeneration. Researchers are exploring the use of this protein in tissue engineering and wound healing applications.

Conclusion

In summary, Recombinant Human KRT20, N-His is a protein with a well-defined structure and important functions in cell structure and signaling. Its overexpression in certain types of cancer makes it a promising drug target, and its potential applications in drug delivery and regenerative medicine make it a valuable protein for scientific research. With further studies, Recombinant Human KRT20, N-His may prove to be a valuable tool in the development of new drugs and treatments for various diseases.

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