Anti-HAO1 Polyclonal Antibody

Anti-HAO1 Polyclonal Antibody

The Anti-HAO1 Polyclonal Antibody is a highly reliable and specific tool for the detection of HAO1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminus of human HAO1 protein.

Biological Function:
HAO1, also known as Hydroxyacid Oxidase 1, is an enzyme that plays a crucial role in the metabolism of fatty acids and amino acids. It catalyzes the oxidation of L-2-hydroxy acids to alpha-keto acids, which are essential for energy production and biosynthesis of important cellular components.

Main Applications:
The Anti-HAO1 Polyclonal Antibody is widely used in various research applications, including western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for studying HAO1 protein expression and function in different species.

Experimental Use Cases:
– Detection of HAO1 protein expression in different tissues and cell lines: The Anti-HAO1 Polyclonal Antibody has been successfully used to detect HAO1 protein levels in various tissues, including liver, kidney, and brain. It has also been used to study HAO1 expression in different cell lines, such as HepG2, HEK293, and MCF7.
– Investigation of HAO1 involvement in metabolic disorders: HAO1 has been linked to several metabolic disorders, including type 2 diabetes and non-alcoholic fatty liver disease. Using the Anti-HAO1 Polyclonal Antibody, researchers can investigate the role of HAO1 in these diseases and potentially identify new therapeutic targets.
– Analysis of HAO1 activity in drug metabolism: HAO1 is involved in the metabolism of certain drugs, such as ibuprofen and valproic acid. By using the Anti-HAO1 Polyclonal Antibody, researchers can study the effect of these drugs on HAO1 expression and activity, providing valuable insights for drug development and personalized medicine.

In summary, the Anti-HAO1 Polyclonal Antibody is a highly specific and reliable tool for studying the biological function and expression of HAO1 protein. Its versatility and proven performance make it an essential reagent for researchers in the fields of metabolism, drug discovery, and disease research. Order now and advance your research with confidence.