Title: Anti-Human ITGA11/Integrin α11 Antibody (SAA1981), PE: A Powerful Tool for Targeting Integrin α11 in Biotech Research
Integrins are a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signaling. Among them, Integrin α11 is a key player in various biological processes, including tissue repair, fibrosis, and cancer progression. To aid in the study of Integrin α11, our team has developed the Anti-Human ITGA11/Integrin α11 Antibody (SAA1981), PE, a highly specific and sensitive antibody that targets Integrin α11 with unparalleled precision.
Biological Function:
Integrin α11, also known as α11β1, is a collagen-binding integrin that is primarily expressed in stromal cells, such as fibroblasts and myofibroblasts. It plays a critical role in the interaction between cells and the extracellular matrix, helping to maintain tissue integrity and regulate cell behavior. Integrin α11 has been implicated in the development and progression of various diseases, making it a promising target for biotech research.
Main Applications:
The Anti-Human ITGA11/Integrin α11 Antibody (SAA1981), PE, is a valuable tool for studying Integrin α11 in a variety of applications. It can be used for:
1. Immunofluorescence: The antibody is conjugated with PE, a fluorescent dye that allows for easy visualization of Integrin α11 in tissue sections or cell cultures.
2. Flow Cytometry: The high specificity and sensitivity of the antibody make it ideal for detecting and quantifying Integrin α11 expression on the surface of cells.
3. Western Blot: The antibody can be used to detect Integrin α11 in protein lysates, providing valuable insights into its expression and regulation.
Experimental Use Cases:
The Anti-Human ITGA11/Integrin α11 Antibody (SAA1981), PE, has been extensively validated in various experimental settings, including:
1. Investigating fibrosis: Integrin α11 has been shown to play a critical role in the development of fibrosis, making it an attractive target for potential therapies. The antibody has been used to study the expression and function of Integrin α11 in fibrotic tissues, providing valuable insights into its role in this disease.
2. Cancer research: Integrin α11 has been implicated in the progression of various cancers, including breast, lung, and pancreatic cancer. The antibody has been used to study its expression in tumor tissues and its potential as a therapeutic target.
3. Tissue repair: Integrin α11 is essential for tissue repair and wound healing. The antibody has been used to study its expression and function in different models of tissue injury, providing valuable insights into its role in the healing process.
In conclusion, the Anti-Human ITGA11/Integrin α11 Antibody (SAA1981), PE, is a powerful tool for studying Integrin α11 in biotech research. Its high specificity, sensitivity, and versatility make it an essential reagent for any researcher interested in understanding the role of Integrin α11 in various biological processes and diseases. Order now and take your research to the next level!
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