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Brand: ProteoGenix

Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679)

Clonality:
Monoclonal Antibody

Original price was: $487.00.Current price is: $393.00.

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Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679)

Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679)

Product name ARO-A23116-100
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Aliases /Synonyms Anti-Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Ccl20, Larc, Liver and activation-regulated chemokine, MIP-3-alpha, Macrophage inflammatory protein 3 alpha, Scya20, Small-inducible cytokine A20
Clonality Monoclonal Antibody
Protein Name Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Ccl20, Larc, Liver and activation-regulated chemokine, MIP-3-alpha, Macrophage inflammatory protein 3 alpha, Scya20, Small-inducible cytokine A20
Product name ARO-A23116-1MG
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Aliases /Synonyms Anti-Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Ccl20, Larc, Liver and activation-regulated chemokine, MIP-3-alpha, Macrophage inflammatory protein 3 alpha, Scya20, Small-inducible cytokine A20
Clonality Monoclonal Antibody
Protein Name Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Ccl20, Larc, Liver and activation-regulated chemokine, MIP-3-alpha, Macrophage inflammatory protein 3 alpha, Scya20, Small-inducible cytokine A20
Product name ARO-A23116-50
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Aliases /Synonyms Anti-Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Ccl20, Larc, Liver and activation-regulated chemokine, MIP-3-alpha, Macrophage inflammatory protein 3 alpha, Scya20, Small-inducible cytokine A20
Clonality Monoclonal Antibody
Protein Name Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Ccl20, Larc, Liver and activation-regulated chemokine, MIP-3-alpha, Macrophage inflammatory protein 3 alpha, Scya20, Small-inducible cytokine A20

Introduction to Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679)

Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) is a monoclonal antibody that specifically targets the chemokine CCL20, also known as MIP-3-alpha. This antibody is widely used in research and has potential applications in various fields, including immunology, oncology, and infectious diseases. In this article, we will provide a comprehensive scientific description of the structure, activity, and potential applications of Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679).

Structure of Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679)

Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) is a monoclonal antibody that is produced by hybridoma technology. It is a mouse IgG2a isotype antibody with a molecular weight of approximately 150 kDa. The antibody is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains consist of four constant domains (CH1, CH2, CH3, and CH4) and one variable domain (VH), while the light chains consist of two constant domains (CL and CL2) and one variable domain (VL). The variable domains of the heavy and light chains are responsible for binding to the target antigen, CCL20.

Activity of Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679)

Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) specifically binds to CCL20, a chemokine that is involved in the recruitment and activation of immune cells. CCL20 is mainly produced by epithelial cells and has been implicated in various physiological and pathological processes, including inflammation, wound healing, and cancer progression. By binding to CCL20, Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) can neutralize its activity and inhibit its binding to its receptors, CCR6 and CCR10. This can prevent the recruitment and activation of immune cells, which can have a therapeutic effect in various diseases.

Applications of Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679)

Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) has a wide range of applications in research and potential therapeutic applications. Some of the key applications of this antibody are discussed below.

1. Immunology: CCL20 is known to play a critical role in immune cell recruitment and activation. Therefore, Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) can be used to study the role of CCL20 in various immune-mediated diseases, such as inflammatory bowel disease, psoriasis, and rheumatoid arthritis. It can also be used to investigate the role of CCL20 in immune cell trafficking in different tissues.

2. Oncology: CCL20 has been shown to promote tumor growth and metastasis by recruiting immune cells to the tumor microenvironment. Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) can inhibit this process and potentially have a therapeutic effect in cancer. It can also be used to study the role of CCL20 in tumor progression and metastasis.

3. Infectious diseases: CCL20 is involved in the recruitment of immune cells to sites of infection and is therefore a potential target for the treatment of infectious diseases. Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) can inhibit the recruitment of immune cells and potentially have a therapeutic effect in infectious diseases, such as tuberculosis and HIV.

4. Inflammation: CCL20 is a potent chemoattractant for immune cells, and its overexpression has been linked to various inflammatory conditions. Anti-Mouse CCL20/MIP-3-alpha Antibody (SAA2679) can neutralize the activity of CCL20 and potentially have a therapeutic

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