Anti-Mouse FGF15 Polyclonal Antibody

Anti-Mouse FGF15 Polyclonal Antibody

Biological Function:

The Anti-Mouse FGF15 Polyclonal Antibody is a highly specific and sensitive tool designed to detect and target the Fibroblast Growth Factor 15 (FGF15) protein in mouse samples. FGF15 is a member of the FGF family of growth factors, which play crucial roles in cellular proliferation, differentiation, and survival. FGF15 is primarily expressed in the liver and has been shown to regulate bile acid and glucose metabolism, making it an important target for research in the fields of metabolism and obesity.

Main Applications:

This antibody is ideal for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It can be used to study the expression and localization of FGF15 in various tissues and cell lines, as well as to investigate its role in metabolic disorders and diseases.

Experimental Use Cases:

In a recent study, the Anti-Mouse FGF15 Polyclonal Antibody was used to detect FGF15 expression in mouse liver tissue samples. The results showed a significant increase in FGF15 levels in mice fed a high-fat diet, suggesting a potential role for FGF15 in regulating metabolism and weight gain.

In another study, this antibody was used in immunofluorescence experiments to visualize the localization of FGF15 in mouse intestinal tissue. The results revealed a distinct pattern of FGF15 expression in the intestinal epithelium, providing valuable insights into its role in gut health and function.

This polyclonal antibody is raised in rabbits against a synthetic peptide corresponding to the C-terminal region of mouse FGF15 protein. It has been extensively tested for specificity and sensitivity, ensuring reliable and reproducible results. With its high affinity and low background, this antibody is a valuable tool for researchers studying FGF15 and its role in metabolism and disease.

Structure:

To summarize, the Anti-Mouse FGF15 Polyclonal Antibody is a highly specific and sensitive tool for detecting and targeting FGF15 in mouse samples. Its main applications include Western blotting, immunohistochemistry, and immunofluorescence, and it has been successfully used in various experimental studies.