Recombinant Human S100A13, N-His

Description of Recombinant Human S100A13, N-His

Introduction

Recombinant Human S100A13 is a protein that plays a crucial role in various cellular processes. It belongs to the S100 protein family, which is a group of small calcium-binding proteins that are involved in regulating several cellular functions. S100A13 is specifically involved in the regulation of intracellular calcium levels and has been found to be associated with various diseases. In this article, we will discuss the structure, activity, and applications of Recombinant Human S100A13.

Structure of Recombinant Human S100A13

Recombinant Human S100A13 is a 10.5 kDa protein composed of 97 amino acids. It has a unique structure consisting of two EF-hand calcium-binding domains connected by a flexible linker region. The EF-hand domains are responsible for binding calcium ions, which is essential for the function of S100A13. The flexible linker region allows for conformational changes in the protein, which is crucial for its activity.

Activity of Recombinant Human S100A13

Recombinant Human S100A13 has been found to be involved in various cellular processes, including cell growth, differentiation, and apoptosis. It is primarily known for its role in regulating intracellular calcium levels. S100A13 binds to calcium ions and regulates their concentration in the cell. This is important for maintaining cellular homeostasis and for the proper functioning of various enzymes and proteins.

Apart from its role in calcium regulation, Recombinant Human S100A13 has been found to interact with other proteins, such as annexin A2 and fibronectin. These interactions are essential for the function of S100A13 in cell adhesion and migration. S100A13 has also been shown to be involved in the regulation of gene expression and protein synthesis, making it a crucial player in cellular processes.

Applications of Recombinant Human S100A13

Recombinant Human S100A13 has a wide range of applications in both research and clinical settings. Its role in regulating calcium levels makes it a valuable tool for studying cellular processes that are influenced by calcium signaling. It has been used in various studies to investigate the role of S100A13 in diseases such as cancer, Alzheimer’s, and cardiovascular diseases.

In addition, Recombinant Human S100A13 has been used as an antigen in vaccine development. Its ability to interact with other proteins and regulate gene expression makes it a potential target for therapeutic interventions. It has also been studied for its potential as a biomarker for various diseases, as its levels have been found to be altered in certain conditions.

Conclusion

In summary, Recombinant Human S100A13 is a small calcium-binding protein with a unique structure and diverse functions. It plays a crucial role in regulating calcium levels and is involved in various cellular processes. Its potential as a biomarker and therapeutic target makes it an important protein in disease research. Further studies on the structure and activity of Recombinant Human S100A13 may lead to a better understanding of its role in disease and potential for therapeutic interventions.