Human NECTIN4-PVRL4 recombinant protein

Reference: PX-P6108-100
Product nameHuman NECTIN4-PVRL4 recombinant protein
Uniprot IDQ96NY8
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
Molecular weight38.41 kDa
Protein delivered with Tag?C-Terminal His Tag
Purity estimated>85% by SDS-PAGE
Buffer0.01M PBS, pH 7.4.
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesMammalian cells
ApplicationsELISA,WB
Fragment TypeMet1-Ser349
Aliases /SynonymsLNIR, NECTIN4, PRR4, Poliovirus receptor-related protein 4, Nectin cell adhesion molecule 4, Ig superfamily receptor LNIR, Nectin-4, PVRL4, Drug Target
ReferencePX-P6108
NoteFor research use only

Description of Human NECTIN4-PVRL4 recombinant protein

General information on Human NECTIN4-PVRL4 recombinant protein

Structure

Human NECTIN4-PVRL4 recombinant protein is a type I transmembrane glycoprotein composed of two extracellular immunoglobulin-like domains, a single transmembrane domain, and a short cytoplasmic tail. It is expressed on the cell surface of various epithelial cells.

Activity

The NECTIN4-PVRL4 protein is involved in cell-cell adhesion, cell-matrix adhesion, and cell-signaling processes. It is also involved in the regulation of cell proliferation, migration, and differentiation.

Application

Human NECTIN4-PVRL4 recombinant protein is used in research to study the role of NECTIN4-PVRL4 in diseases such as cancer, inflammation, and immune-related disorders. It is also used as an antibody-drug target for the development of novel therapeutics.

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