Recombinant Human FXR1 Protein, N-His

Description of Recombinant Human FXR1 Protein, N-His

Introduction

Recombinant Human FXR1 Protein, also known as Fragile X-related protein 1, is a member of the Fragile X gene family and is encoded by the FXR1 gene. This protein is involved in a variety of cellular processes, including RNA binding, translation regulation, and cell signaling. In this article, we will explore the structure, activity, and applications of Recombinant Human FXR1 Protein.

Structure of Recombinant Human FXR1 Protein

Recombinant Human FXR1 Protein is a 70-kDa protein consisting of 632 amino acids. It contains three highly conserved domains, including an N-terminal RNA-binding domain, a central RGG domain, and a C-terminal protein-protein interaction domain. This protein also has several phosphorylation sites, which play a crucial role in its activity.

The RNA-binding domain of Recombinant Human FXR1 Protein is responsible for its interaction with RNA molecules, including mRNA, tRNA, and rRNA. The RGG domain, on the other hand, is involved in protein-protein interactions, particularly with other members of the Fragile X gene family. The C-terminal domain of this protein is essential for its localization to specific subcellular compartments, such as the nucleus, cytoplasm, and stress granules.

Activity of Recombinant Human FXR1 Protein

Recombinant Human FXR1 Protein is a multifunctional protein with diverse activities in various cellular processes. One of its primary functions is its role in RNA binding and translation regulation. This protein has been shown to interact with multiple RNA-binding proteins, including ribosomes, mRNA, and microRNAs, to regulate translation and protein synthesis.

Moreover, Recombinant Human FXR1 Protein is involved in cell signaling pathways, particularly those related to stress response and cell survival. It has been shown to interact with several signaling molecules, such as MAP kinases and PI3K, to regulate cell growth and survival. This protein also plays a crucial role in neuronal development and synaptic plasticity, making it a potential target for neurological disorders.

Applications of Recombinant Human FXR1 Protein

Recombinant Human FXR1 Protein has various applications in both research and clinical settings. Its ability to bind to RNA molecules makes it a valuable tool for studying RNA-protein interactions and translation regulation. This protein has also been used in the development of diagnostic assays for Fragile X syndrome, a genetic disorder caused by mutations in the FXR1 gene.

Furthermore, Recombinant Human FXR1 Protein has shown promising results in the treatment of various diseases. Its role in cell signaling and stress response makes it a potential target for cancer therapy, as it can inhibit cell growth and promote cell death. This protein has also been studied for its potential in treating neurological disorders, such as Fragile X syndrome and autism spectrum disorders.

Conclusion

In conclusion, Recombinant Human FXR1 Protein is a multifunctional protein with diverse roles in cellular processes. Its structure, consisting of three highly conserved domains, allows it to interact with various molecules and participate in RNA binding, translation regulation, and cell signaling. This protein has numerous applications in research and clinical settings, making it a valuable tool for understanding and treating various diseases.