Azirkitug Biosimilar – Anti-CKR-L1 mAb – Research Grade

Reference:
Product nameAzirkitug Biosimilar - Anti-CKR-L1 mAb - Research Grade
SourceCAS: 2837169-12-5
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-CKR-L1, CMKBR8, C-C CKR-8, GPR-CY6, CCR8, CMKBRL2, TER1, CCR-8, Chemokine receptor-like 1, CKRL1, CDw198, GPRCY6, C-C chemokine receptor type 8, CC-CKR-8, CC chemokine receptor CHEMR1
ReferencePX-TA2173-100
NoteFor research use only. Not suitable for human use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody

Description of Azirkitug Biosimilar - Anti-CKR-L1 mAb - Research Grade

Introduction

Azirkitug Biosimilar – Anti-CKR-L1 mAb is a therapeutic antibody that has shown promising results in the treatment of various diseases. This biosimilar is a monoclonal antibody that targets the CKR-L1 protein, which is involved in various cellular processes and has been linked to several diseases. In this article, we will explore the structure, activity, and potential applications of Azirkitug Biosimilar – Anti-CKR-L1 mAb.

Structure of Azirkitug Biosimilar – Anti-CKR-L1 mAb

Azirkitug Biosimilar – Anti-CKR-L1 mAb is a monoclonal antibody that is produced in a laboratory setting. It is a protein made up of two heavy chains and two light chains, with a total molecular weight of approximately 150 kDa. The heavy and light chains are held together by disulfide bonds, forming a Y-shaped structure.

The variable regions of the antibody, also known as the antigen-binding sites, are located at the tips of the Y-shaped structure. These regions are responsible for binding to the CKR-L1 protein, while the constant regions of the antibody are responsible for activating various immune responses.

Activity of Azirkitug Biosimilar – Anti-CKR-L1 mAb

The main activity of Azirkitug Biosimilar – Anti-CKR-L1 mAb is to bind to the CKR-L1 protein and block its function. CKR-L1 is a chemokine receptor that is involved in the migration and activation of immune cells. It has been found to be overexpressed in various diseases, including cancer, autoimmune disorders, and inflammatory diseases.

By binding to CKR-L1, Azirkitug Biosimilar – Anti-CKR-L1 mAb inhibits its function and prevents the recruitment and activation of immune cells. This leads to a decrease in inflammation and disease progression.

In addition to its direct activity against CKR-L1, Azirkitug Biosimilar – Anti-CKR-L1 mAb also has an indirect activity through its interaction with immune cells. The constant region of the antibody can bind to Fc receptors on immune cells, leading to their activation and recruitment to the site of disease.

Applications of Azirkitug Biosimilar – Anti-CKR-L1 mAb

The therapeutic antibody, Azirkitug Biosimilar – Anti-CKR-L1 mAb, has shown potential in the treatment of various diseases. Its main application is in the treatment of cancer, where CKR-L1 has been found to be overexpressed in many types of tumors. By targeting CKR-L1, Azirkitug Biosimilar – Anti-CKR-L1 mAb can inhibit tumor growth and metastasis, as well as enhance the effectiveness of other cancer treatments.

In addition to cancer, Azirkitug Biosimilar – Anti-CKR-L1 mAb has also shown promise in the treatment of autoimmune disorders and inflammatory diseases. By blocking the function of CKR-L1, this therapeutic antibody can reduce inflammation and prevent tissue damage in these conditions.

Furthermore, Azirkitug Biosimilar – Anti-CKR-L1 mAb can also be used in research settings to study the role of CKR-L1 in various diseases and to develop new treatments targeting this protein.

Conclusion

In conclusion, Azirkitug Biosimilar – Anti-CKR-L1 mAb is a promising therapeutic antibody that targets the CKR-L1 protein. Its structure, activity, and potential applications make it a valuable tool in the treatment of various diseases, particularly cancer, autoimmune disorders, and inflammatory diseases. Further research and clinical trials are needed to fully understand the potential of this biosimilar and its role in improving patient outcomes.

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