Monkeypox virus/MPXV H3L Monoclonal Antibody SAA0282

Reference: PTX18820-100
Product nameMonkeypox virus/MPXV H3L Monoclonal Antibody SAA0282
FormLiquid in PBS buffer, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
BrandProteoGenix
Host speciesMouse
ReactivityMonkeypox virus(MPXV)
ReferencePTX18820
IsotypeIgG2a, kappa
ClonalityMonoclonal Antibody
ImmunogenH3L
Clone NameSAA0282
Protein NameH3L
Target speciesAnti-Monkeypox virus(MPXV) Monoclonal Antibody

Description of Monkeypox virus/MPXV H3L Monoclonal Antibody SAA0282

Monkeypox Virus H3L Monoclonal Antibody

Structure

Monkeypox virus H3L monoclonal antibodies are IgG immunoglobulins, which consist of two heavy chains and two light chains. Each heavy chain contains four domains, and each light chain contains two domains. The antibody binds to the antigen of the monkeypox virus, which is the H3L protein.

Activity

Monkeypox virus H3L monoclonal antibodies are highly specific and bind to the H3L protein of the virus. This binding inhibits the virus from entering cells, thus preventing infection. The antibodies also trigger the body’s immune system to produce anti-viral proteins that can clear the virus from the body.

Application

Monkeypox virus H3L monoclonal antibodies are used for research purpose only in monkeypox virus infections. The antibodies are used to study the structure and function of the virus.

SDS PAGE for Monkeypox virus/MPXV H3L Antibody (SAA0282)

Monkeypox virus/MPXV H3L Monoclonal Antibody SAA0282, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Publication

Zuiani et al., A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease, 2024, Cell 187, 1–11March 14, 2024 https://doi.org/10.1016/j.cell.2024.01.017

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