Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284

Reference: PTX18822-100
Product nameMonkeypox virus/MPXV M1R Monoclonal Antibody SAA0284
FormLiquid in PBS buffer, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
BrandProteoGenix
Host speciesMouse
ReactivityMonkeypox virus(MPXV)
ReferencePTX18822
IsotypeIgG2a, kappa
ClonalityMonoclonal Antibody
ImmunogenM1R
Clone NameSAA0284
Protein NameM1R
Target speciesAnti-Monkeypox virus(MPXV) Monoclonal Antibody

Description of Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284

Structure of Monkeypox Virus M1R Monoclonal Antibody

Monkeypox virus M1R monoclonal antibody is a type of IgG1 antibody, which is composed of two heavy chains and two light chains. Each chain contains a variable region that is specific for the target antigen, and a constant region that is responsible for binding to the B-cell receptor and other molecules involved in the immune response.

Activity of Monkeypox Virus M1R Monoclonal Antibody

The M1R monoclonal antibody binds to the surface of the monkeypox virus, preventing it from entering the cells of the host organism. This prevents the virus from replicating and spreading, thus providing protection against infection.

Application of Monkeypox Virus M1R Monoclonal Antibody

The M1R monoclonal antibody can be used for research purpose only in monkeypox virus infections.

Detects Monkeypox virus/MPXV M1R in direct ELISAs.

SDS-PAGE for Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284

Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Publication

Zuiani et al., A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease, 2024, Cell 187, 1–11March 14, 2024 https://doi.org/10.1016/j.cell.2024.01.017

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