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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG2a-nd; IgG1-nd |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | Mammalian cells |
| Applications | Elisa, WB |
| Product name | 4F2Mab Biosimilar - Anti-ganglioside GD2, SFRP1, SLC3A2 mAb - Research Grade |
|---|---|
| Species | Humanized |
| Purity | >85% |
| Buffer | PBS buffer PH7.5 |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | 4F2Mab,14G2a,4F2,ganglioside GD2, SFRP1, SLC3A2,anti-ganglioside GD2, SFRP1, SLC3A2 |
| Reference | PX-TA1073 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG2a-nd; IgG1-nd |
| Clonality | Monoclonal Antibody |
4F2Mab Biosimilar is a monoclonal antibody (mAb) that targets three different proteins – ganglioside GD2, secreted frizzled-related protein 1 (SFRP1), and solute carrier family 3 member 2 (SLC3A2). These proteins have been identified as potential therapeutic targets for various diseases and conditions, making 4F2Mab Biosimilar a promising candidate for research and development.
4F2Mab Biosimilar is a recombinant mAb that is produced through genetic engineering techniques. It is a chimeric antibody, meaning it contains both human and mouse components. The variable regions of the antibody are derived from mouse antibodies, while the constant regions are of human origin. This allows for a more specific binding to the target proteins, while also reducing the risk of immune reactions in patients.
The primary mechanism of action of 4F2Mab Biosimilar is through binding to its target proteins, ganglioside GD2, SFRP1, and SLC3A2. This binding can lead to various downstream effects, depending on the specific target and the disease or condition being treated. For example, binding to ganglioside GD2 can trigger immune-mediated cytotoxicity, leading to the destruction of tumor cells. On the other hand, binding to SFRP1 can inhibit the Wnt signaling pathway, which is involved in tumor growth and metastasis.
4F2Mab Biosimilar has shown potential in the treatment of various diseases and conditions. One of the primary applications of this mAb is in the treatment of cancer. Ganglioside GD2 is overexpressed in many types of cancer, including neuroblastoma, melanoma, and small cell lung cancer. By targeting this protein, 4F2Mab Biosimilar can potentially inhibit tumor growth and improve patient outcomes.
In addition to cancer, 4F2Mab Biosimilar has also shown promise in the treatment of autoimmune diseases. SFRP1 has been implicated in the development of autoimmune disorders such as rheumatoid arthritis and multiple sclerosis. By blocking the Wnt signaling pathway, 4F2Mab Biosimilar can potentially reduce inflammation and improve symptoms in these conditions.
4F2Mab Biosimilar is currently available as a research grade product, meaning it is intended for laboratory use only. However, with further research and development, it has the potential to become a therapeutic option for patients. Clinical trials are currently underway to evaluate the safety and efficacy of this mAb in various diseases, and the results so far have been promising.
In summary, 4F2Mab Biosimilar is a chimeric mAb that targets three different proteins – ganglioside GD2, SFRP1, and SLC3A2. Its unique structure and mechanism of action make it a promising candidate for the treatment of cancer and autoimmune diseases. With ongoing research and development, 4F2Mab Biosimilar has the potential to provide new treatment options for patients in the future.
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