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4F2Mab Biosimilar – Anti-ganglioside GD2, SFRP1, SLC3A2 mAb – Research Grade

Reference:
Size

100ug, 1MG

Isotype

IgG2a-nd; IgG1-nd

Brand

ProteoGenix

Product type

Primary Antibodies

Clonality

Monoclonal Antibody

Expression system

Mammalian cells

Applications

Elisa, WB

Product name4F2Mab Biosimilar - Anti-ganglioside GD2, SFRP1, SLC3A2 mAb - Research Grade
SpeciesHumanized
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /Synonyms4F2Mab,14G2a,4F2,ganglioside GD2, SFRP1, SLC3A2,anti-ganglioside GD2, SFRP1, SLC3A2
ReferencePX-TA1073
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG2a-nd; IgG1-nd
ClonalityMonoclonal Antibody

Description of 4F2Mab Biosimilar - Anti-ganglioside GD2, SFRP1, SLC3A2 mAb - Research Grade

Introduction to 4F2Mab Biosimilar – Anti-ganglioside GD2, SFRP1, SLC3A2 mAb

4F2Mab Biosimilar is a monoclonal antibody (mAb) that targets three different proteins – ganglioside GD2, secreted frizzled-related protein 1 (SFRP1), and solute carrier family 3 member 2 (SLC3A2). These proteins have been identified as potential therapeutic targets for various diseases and conditions, making 4F2Mab Biosimilar a promising candidate for research and development.

Structure of 4F2Mab Biosimilar

4F2Mab Biosimilar is a recombinant mAb that is produced through genetic engineering techniques. It is a chimeric antibody, meaning it contains both human and mouse components. The variable regions of the antibody are derived from mouse antibodies, while the constant regions are of human origin. This allows for a more specific binding to the target proteins, while also reducing the risk of immune reactions in patients.

Mechanism of Action

The primary mechanism of action of 4F2Mab Biosimilar is through binding to its target proteins, ganglioside GD2, SFRP1, and SLC3A2. This binding can lead to various downstream effects, depending on the specific target and the disease or condition being treated. For example, binding to ganglioside GD2 can trigger immune-mediated cytotoxicity, leading to the destruction of tumor cells. On the other hand, binding to SFRP1 can inhibit the Wnt signaling pathway, which is involved in tumor growth and metastasis.

Title: Applications of 4F2Mab Biosimilar

4F2Mab Biosimilar has shown potential in the treatment of various diseases and conditions. One of the primary applications of this mAb is in the treatment of cancer. Ganglioside GD2 is overexpressed in many types of cancer, including neuroblastoma, melanoma, and small cell lung cancer. By targeting this protein, 4F2Mab Biosimilar can potentially inhibit tumor growth and improve patient outcomes.

In addition to cancer, 4F2Mab Biosimilar has also shown promise in the treatment of autoimmune diseases. SFRP1 has been implicated in the development of autoimmune disorders such as rheumatoid arthritis and multiple sclerosis. By blocking the Wnt signaling pathway, 4F2Mab Biosimilar can potentially reduce inflammation and improve symptoms in these conditions.

Title: Research Grade and Future Developments

4F2Mab Biosimilar is currently available as a research grade product, meaning it is intended for laboratory use only. However, with further research and development, it has the potential to become a therapeutic option for patients. Clinical trials are currently underway to evaluate the safety and efficacy of this mAb in various diseases, and the results so far have been promising.

Conclusion

In summary, 4F2Mab Biosimilar is a chimeric mAb that targets three different proteins – ganglioside GD2, SFRP1, and SLC3A2. Its unique structure and mechanism of action make it a promising candidate for the treatment of cancer and autoimmune diseases. With ongoing research and development, 4F2Mab Biosimilar has the potential to provide new treatment options for patients in the future.

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