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100ug, 1MG
ProteoGenix
Primary Antibodies
Monoclonal Antibody
Mammalian cells
Elisa, WB
Adalimumab is a human IgG1 monoclonal antibody that is recombinant and that targets against tumor necrosis factor-alpha (TNF-alpha). This antibody has immunomodulating properties. Adalimumab attaches to TNF-alpha, effectively blocking its interaction with the p55 and p75 TNF cell surface receptors, consequently hindering TNF-mediated immune reactions. TNF-alpha, is an inflammatory cytokine. It is especially involved in autoimmune conditions.
Immobilized Human TNFa Recombinant Protein (cat. No. PX-P3058) at 0.5µg/mL (100µL/well) can bind Adalimumab Biosimilar - Anti-TNF alpha mAb (cat. No. PX-TA1001) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 142.1M.
Adalimumab Biosimilar - Anti-TNF alpha mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.
Reviews
Ofer Gover – December 14, 2021
We used this ab to reduce as a negative control for reducing caco-2 (IEC) cells exitation by exugenues TNFa. We measured IL8 secreation as a result of TNFa stimulation. 1ug/mL ofAdalimumab Biosimilar – Anti-TNF alpha mAb was enough to completly abolish IL8 secreation by TNFa stimulation in caco-2 cells.
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300µL
100ug