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Brand: ProteoGenix

Mouse PAD4 protein-arginine deiminase type-4 Recombinant Protein

Uniprot ID:
Q9Z183
Molecular weight:
77.52kDa

$500.00

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Full-length Yes
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Mouse PAD4 protein-arginine deiminase type-4 Recombinant Protein

Mouse PAD4 protein-arginine deiminase type-4 Recombinant Protein

Product name Mouse PAD4 protein-arginine deiminase type-4 Recombinant Protein
Uniprot ID Q9Z183
Uniprot link https://www.uniprot.org/uniprot/Q9Z183
Origin species House Mouse
Expression system Eukaryotic expression
Sequence MGASWSHPQFEKGGGSGGGSGGSAWSHPQFEKMAQGAVIHVAPEQPTHAVCVVGTATPLDVRGSAPKGYTTFGITASPGVIVDVIHGPPVKKSTMGASKWPLDPELEVTLQVKAASSRTDDEKVRVSYYGPKTSPVQALIYITGVELSLSADVTRTGRVKPAQAGKDQSTWTWGPGGRGAILLVNCDKEDPQASGMDFEDDKILDNKDLQDMSPMTLSTKTPKDFFEKYQLVLEVPKAKMNRVRVFRATRGKLPSRYKVALGPQQFSYCLELPGGQHSTDFYVEGLAFPDADFKGLIPLTISLLDKSNPELPEALVFQDSVTFRVAPWIMTPNTQPPQEVYVCRVSDNEDFLKSLATLTKKAKCKLTVCPEEENIDDQWMQDEMEIGYIQAPHKTLPVVFDSPRDRGLKDFPVKRVMGPNFGYVTRKLYMSELTGLDAFGNLEVSPPVTVRGKEYPLGRILIGNSGYSSSESRDMHQALQDFLSAQQVQAPVRLFSDWLFVGHVDEFLSFVPARDKQGFRLLLSSPRACYQLFQELQSQGHGEATLFEGLKRKRQTINEILSNKKLRDQNAYVESCIDWNRAVLKRELGLAEGDIIDIPQLFKLAGNSRGNSKAQAFFPNMVNMLVLGKYLGIPKPFGPIIDGHCCLEEEVRSHLEPLGLHCTFINDFYTYHVYNGEVHCGTNVRRKPFTFKWWHMVP
Molecular weight 77.52kDa
Protein delivered with Tag? Yes
Purity estimated 90%
Buffer 50mM Tris-Cl pH 8.0, 150mM NaCl
Form Frozen
Delivery condition Dry Ice
Delivery lead time in business days 10-25
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Insect
Fragment Type Full-length
Protein Accession NP_035191.2
Spec:Entrez GeneID 18602
Spec:NCBI Gene Aliases Pad4, Pdi4，Padi4
Spec:SwissProtID Q9Z183
NCBI Reference NP_035191.2
Aliases /Synonyms Pad4, Pdi4，Padi4，Peptidylarginine deiminase IV,Protein-arginine deiminase type IV
Reference PX-P4068
Note For research use only
Molecular Constructor
Full-length Yes
Product name Mouse PAD4 protein-arginine deiminase type-4 Recombinant Protein
Uniprot ID Q9Z183
Uniprot link https://www.uniprot.org/uniprot/Q9Z183
Origin species House Mouse
Expression system Eukaryotic expression
Sequence MGASWSHPQFEKGGGSGGGSGGSAWSHPQFEKMAQGAVIHVAPEQPTHAVCVVGTATPLDVRGSAPKGYTTFGITASPGVIVDVIHGPPVKKSTMGASKWPLDPELEVTLQVKAASSRTDDEKVRVSYYGPKTSPVQALIYITGVELSLSADVTRTGRVKPAQAGKDQSTWTWGPGGRGAILLVNCDKEDPQASGMDFEDDKILDNKDLQDMSPMTLSTKTPKDFFEKYQLVLEVPKAKMNRVRVFRATRGKLPSRYKVALGPQQFSYCLELPGGQHSTDFYVEGLAFPDADFKGLIPLTISLLDKSNPELPEALVFQDSVTFRVAPWIMTPNTQPPQEVYVCRVSDNEDFLKSLATLTKKAKCKLTVCPEEENIDDQWMQDEMEIGYIQAPHKTLPVVFDSPRDRGLKDFPVKRVMGPNFGYVTRKLYMSELTGLDAFGNLEVSPPVTVRGKEYPLGRILIGNSGYSSSESRDMHQALQDFLSAQQVQAPVRLFSDWLFVGHVDEFLSFVPARDKQGFRLLLSSPRACYQLFQELQSQGHGEATLFEGLKRKRQTINEILSNKKLRDQNAYVESCIDWNRAVLKRELGLAEGDIIDIPQLFKLAGNSRGNSKAQAFFPNMVNMLVLGKYLGIPKPFGPIIDGHCCLEEEVRSHLEPLGLHCTFINDFYTYHVYNGEVHCGTNVRRKPFTFKWWHMVP
Molecular weight 77.52kDa
Protein delivered with Tag? Yes
Purity estimated 90%
Buffer 50mM Tris-Cl pH 8.0, 150mM NaCl
Form Frozen
Delivery condition Dry Ice
Delivery lead time in business days 10-25
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Insect
Fragment Type Full-length
Protein Accession NP_035191.2
Spec:Entrez GeneID 18602
Spec:NCBI Gene Aliases Pad4, Pdi4，Padi4
Spec:SwissProtID Q9Z183
NCBI Reference NP_035191.2
Aliases /Synonyms Pad4, Pdi4，Padi4，Peptidylarginine deiminase IV,Protein-arginine deiminase type IV
Reference PX-P4068
Note For research use only
Molecular Constructor
Full-length Yes

General Information nn Mouse PAD4 :

Mouse PAD4 (PADI4) functions as a transcriptional coregulator by catalyzing the conversion of histone H3 arginine residues to citrulline residues. This reaction, known as citrullination, leads to the post-translational modification of proteins.

PADI4 gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PAD4 is mainly expressed in granulocytes, monocytes and CD34+ stem cells. Protein arginine deiminase type-4 was initially cloned from the HL-60 cell line (human promyelocytic leukemia cells). Protein arginine deiminase type-4 may play a role in granulocyte and macrophage development leading to inflammation and immune response. The PADI4 single-nucleotide polymorphism (SNP) and haplotypes were associated with rheumatoid arthritis susceptibility.
Recently, PAD4 has also been found in a variety of malignant tumors and implies its potential roles in tumor genesis.

Eukaryote expression systems and more specifically Insect cells are used at ProteoGenix to produce mouse PAD4 recombinant protein with appropriate post translational modifications.

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