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Brand: ProteoGenix

MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein

Uniprot ID:
Q08642
Molecular weight:
79.36 kDa

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Full-length Yes
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MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein

MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein

Product name MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein
Uniprot ID Q08642
Uniprot link http://www.uniprot.org/uniprot/Q08642
Origin species House Mouse
Expression system Eukaryotic expression
Sequence MGASWSHPQFEKGGGSGGGSGGSAWSHPQFEKMQPPIRENMLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTNGKQRWALSPSSTLRLSMAQASTEASSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLCFPDESFSGLVSIHVSLLEYMAEGIPLTPIFTDTVMFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKEYPLGRILIGSSFPLSGGRRMTKVVRDFLQAQQVQAPVELYSDWLTVGHVDEFMTFIPIPGKKEFRLLMASTSACYQLFREKQKAGHGEAVMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKRELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP
Molecular weight 79.36 kDa
Protein delivered with Tag? Yes
Purity estimated 95%
Buffer 50mM Tris-Cl pH 8.0, 150mM NaCl
Form Lyophilized
Delivery condition Dry Ice
Delivery lead time in business days 2-3
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Insect
Fragment Type Full-length
NCBI Reference NP_032838.2
Biological activity Calcium-dependent critrullination activity of the recombinant PAD2 was confirmed with Fibrinogen as substrate (detection of critrullinated fibrinogen by ELISA).
Aliases /Synonyms PAD-H19, PAD2, PDI2, Peptidylarginine deiminase II
Reference PX-P3022
Note For research use only
Molecular Constructor
Full-length Yes
Product name MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein
Uniprot ID Q08642
Uniprot link http://www.uniprot.org/uniprot/Q08642
Origin species House Mouse
Expression system Eukaryotic expression
Sequence MGASWSHPQFEKGGGSGGGSGGSAWSHPQFEKMQPPIRENMLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTNGKQRWALSPSSTLRLSMAQASTEASSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLCFPDESFSGLVSIHVSLLEYMAEGIPLTPIFTDTVMFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKEYPLGRILIGSSFPLSGGRRMTKVVRDFLQAQQVQAPVELYSDWLTVGHVDEFMTFIPIPGKKEFRLLMASTSACYQLFREKQKAGHGEAVMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKRELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP
Molecular weight 79.36 kDa
Protein delivered with Tag? Yes
Purity estimated 95%
Buffer 50mM Tris-Cl pH 8.0, 150mM NaCl
Form Lyophilized
Delivery condition Dry Ice
Delivery lead time in business days 2-3
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Insect
Fragment Type Full-length
NCBI Reference NP_032838.2
Biological activity Calcium-dependent critrullination activity of the recombinant PAD2 was confirmed with Fibrinogen as substrate (detection of critrullinated fibrinogen by ELISA).
Aliases /Synonyms PAD-H19, PAD2, PDI2, Peptidylarginine deiminase II
Reference PX-P3022
Note For research use only
Molecular Constructor
Full-length Yes

General Information about Mouse PAD2 (PADI2)

Mouse PAD2 (PADI2) is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions.

PADI2 has peptidylarginine deiminase activity against synthetic substrates. PAD2 is mainly expressed in the central nervous system, skeletal muscle, spinal cord, cerebrum, cerebellum, and submaxillary gland. Protein arginine deiminase type-2 plays a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis.

Eukaryote expression systems and more specifically Insect cells are used at ProteoGenix to produce mouse PAD2 recombinant protein with appropriate post translational modifications.

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