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Brand: ProteoGenix

Protein-arginine deiminase type-4(PADI4)

Host species:
Insect
Origin species:
Homo sapiens (Human)
Uniprot ID:
Q9UM07
Molecular weight:
77.29kDa

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Twin-Strep Met1~Pro663
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Protein-arginine deiminase type-4(PADI4)

Product name Protein-arginine deiminase type-4(PADI4)
Uniprot ID Q9UM07
Uniprot link https://www.uniprot.org/uniprot/Q9UM07
Origin species Homo sapiens (Human)
Expression system Eukaryotic expression
Sequence MGASWSHPQFEKGGGSGGGSGGSAWSHPQFEKMAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP
Molecular weight 77.29kDa
Protein delivered with Tag? N-terminal Twin-Strep Tag
Purity estimated >80% by SDS-PAGE
Buffer PBS, pH 7.5
Form Liquid
Delivery condition Dry Ice
Delivery lead time in business days Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Insect
Fragment Type Met1~Pro663
Protein Accession Q9UM07
Spec:Entrez GeneID 23569
Spec:NCBI Gene Aliases PAD; PAD4; PDI4; PDI5; PADI5
NCBI Reference Q9UM07
Aliases /Synonyms PAD4, PADI5, PDI5,HL-60 PAD,Peptidylarginine deiminase IV,Protein-arginine deiminase type IV
Reference PX-P4886
Note For research use only
Molecular Constructor
Twin-Strep Met1~Pro663
Product name Protein-arginine deiminase type-4(PADI4)
Uniprot ID Q9UM07
Uniprot link https://www.uniprot.org/uniprot/Q9UM07
Origin species Homo sapiens (Human)
Expression system Eukaryotic expression
Sequence MGASWSHPQFEKGGGSGGGSGGSAWSHPQFEKMAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP
Molecular weight 77.29kDa
Protein delivered with Tag? N-terminal Twin-Strep Tag
Purity estimated >80% by SDS-PAGE
Buffer PBS, pH 7.5
Form Liquid
Delivery condition Dry Ice
Delivery lead time in business days Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Insect
Fragment Type Met1~Pro663
Protein Accession Q9UM07
Spec:Entrez GeneID 23569
Spec:NCBI Gene Aliases PAD; PAD4; PDI4; PDI5; PADI5
NCBI Reference Q9UM07
Aliases /Synonyms PAD4, PADI5, PDI5,HL-60 PAD,Peptidylarginine deiminase IV,Protein-arginine deiminase type IV
Reference PX-P4886
Note For research use only
Molecular Constructor
Twin-Strep Met1~Pro663

General Information about Mouse PAD4 (PADI4)

PADI4 gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PAD4 is mainly expressed in granulocytes, monocytes and CD34+ stem cells. Protein arginine deiminase type-4 was initially cloned from the HL-60 cell line (human promyelocytic leukemia cells). Protein arginine deiminase type-4 may play a role in granulocyte and macrophage development leading to inflammation and immune response. The PADI4 single-nucleotide polymorphism (SNP) and haplotypes were associated with rheumatoid arthritis susceptibility.
Recently, PAD4 has also been found in a variety of malignant tumors and implies its potential roles in tumor genesis.

Eukaryote expression systems and more specifically Insect cells are used at ProteoGenix to produce mouse PAD4 recombinant protein with appropriate post translational modifications.

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