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Brand: ProteoGenix

Verekitug Biosimilar – Anti-Cytokine receptor-like 2 mAb – Research Grade

  • PX-TA2148-50
  • Validated WB
Clonality:
Monoclonal Antibody
Isotype:
IgG1, kappa

Original price was: $228.00.Current price is: $167.00.

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Verekitug Biosimilar - Anti-Cytokine receptor-like 2 mAb - Research Grade

Product name PX-TA2148-50
Uniprot ID Q9HC73
Source CAS: 2768386-15-6
Origin species Homo sapiens
Expression system XtenCHO
Raw Antigen Sequence MGRLVLLWGAAVFLLGGWMALGQGGAAEGVQIQIIYFNLETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLFEIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIGGFTFVMNDRSYVAL
Purity >95% by SDS-PAGE.
Buffer 0.01M PBS, pH 7.4.
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term; -20°C for long term
Brand ProteoGenix
Reference PX-TA2148
Note For research use only. Not suitable for human use.
Isotype IgG1, kappa
Clonality Monoclonal Antibody
Product name Verekitug Biosimilar - Anti-Cytokine receptor-like 2 mAb - Research Grade
Uniprot ID Q9HC73
Source CAS: 2768386-15-6
Origin species Homo sapiens
Expression system XtenCHO
Raw Antigen Sequence MGRLVLLWGAAVFLLGGWMALGQGGAAEGVQIQIIYFNLETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLFEIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIGGFTFVMNDRSYVAL
Purity >95% by SDS-PAGE.
Buffer 0.01M PBS, pH 7.4.
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term; -20°C for long term
Brand ProteoGenix
Reference PX-TA2148
Note For research use only. Not suitable for human use.
Isotype IgG1, kappa
Clonality Monoclonal Antibody
Product name Verekitug Biosimilar - Anti-Cytokine receptor-like 2 mAb - Research Grade
Uniprot ID Q9HC73
Source CAS: 2768386-15-6
Origin species Homo sapiens
Expression system XtenCHO
Raw Antigen Sequence MGRLVLLWGAAVFLLGGWMALGQGGAAEGVQIQIIYFNLETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLFEIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIGGFTFVMNDRSYVAL
Purity >95% by SDS-PAGE.
Buffer 0.01M PBS, pH 7.4.
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term; -20°C for long term
Brand ProteoGenix
Reference PX-TA2148
Note For research use only. Not suitable for human use.
Isotype IgG1, kappa
Clonality Monoclonal Antibody

Verekitug Biosimilar – An Overview

Verekitug Biosimilar is a research grade monoclonal antibody (mAb) that targets the cytokine receptor-like 2 (CRL2) protein. This biosimilar is designed to mimic the activity of the original anti-CRL2 mAb, providing researchers with a cost-effective and reliable alternative for their studies.

Structure of Verekitug Biosimilar

Verekitug Biosimilar is a recombinant humanized mAb, meaning it is produced by genetically engineering human cells to express the antibody. It is composed of two heavy chains and two light chains, each containing a variable region and a constant region. The variable regions are responsible for binding to the CRL2 protein, while the constant regions provide stability and effector functions.

Activity of Verekitug Biosimilar

The primary function of Verekitug Biosimilar is to bind to the CRL2 protein and block its activity. CRL2 is a type I transmembrane protein that is involved in various cellular processes, including cell proliferation, differentiation, and immune response. By targeting CRL2, Verekitug Biosimilar can modulate these processes and potentially have therapeutic effects.

In addition to blocking CRL2 activity, Verekitug Biosimilar also has effector functions that can activate the immune system and induce cell death in CRL2-expressing cells. This makes it a valuable tool for studying the role of CRL2 in disease and for developing potential treatments.

Application of Verekitug Biosimilar

Verekitug Biosimilar has a wide range of applications in research, particularly in the fields of immunology and oncology. It can be used to study the role of CRL2 in various diseases, such as cancer, autoimmune disorders, and infectious diseases. Researchers can also use Verekitug Biosimilar to screen for potential drugs that target CRL2 or to develop novel therapeutic strategies.

In addition, Verekitug Biosimilar can be used in diagnostic assays to detect levels of CRL2 in patient samples, providing valuable information for disease diagnosis and monitoring. It can also be used in preclinical studies to evaluate the safety and efficacy of potential CRL2-targeting drugs.

Conclusion

Verekitug Biosimilar is a research grade anti-CRL2 mAb that offers a cost-effective and reliable alternative for studying the role of CRL2 in disease. Its unique structure and activity make it a valuable tool for researchers in various fields, and its potential applications are vast. With its ability to block CRL2 activity and induce immune responses, Verekitug Biosimilar has the potential to contribute to the development of new treatments for a range of diseases.

SDS-PAGE for Research Grade Verekitug

SDS-PAGE for Research Grade Verekitug

Research Grade Verekitug, on SDS-PAGE. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

Research Grade Verekitug in WB Assay

Research Grade Verekitug in WB Assay

Research Grade Verekitug can bind to its target in Western Blot Assay as detected on gel analysis.

Verekitug Biosimilar - Anti-Cytokine receptor-like 2 mAb - Research Grade

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