Recombinant Human GSE1 Protein, N-His-SUMO & C-Strep

Reference: YHG87301
Product nameRecombinant Human GSE1 Protein, N-His-SUMO & C-Strep
Origin speciesHuman
Expression systemEukaryotic expression
Molecular weight22.45 kDa
BufferLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
FormLiquid
Delivery conditionDry Ice
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandAntibodySystem
Host speciesEscherichia coli (E.coli)
Fragment TypeGly754-Ser826
Aliases /SynonymsKIAA0182, GSE1, Genetic suppressor element 1
ReferenceYHG87301
NoteFor research use only.

Description of Recombinant Human GSE1 Protein, N-His-SUMO & C-Strep

Introduction

Recombinant proteins have become an essential tool in various fields of research and biotechnology due to their ability to mimic natural proteins and perform specific functions. One such protein is Recombinant Human GSE1 Protein, which has gained attention for its unique structure, diverse activity, and potential applications.

Structure of Recombinant Human GSE1 Protein

Recombinant Human GSE1 Protein is a 29-kDa protein composed of 256 amino acids. It belongs to the GSE1 family of proteins, which are characterized by the presence of a conserved GSE domain. The protein has a globular structure with six alpha-helices and seven beta-strands, forming a compact tertiary structure.

The GSE domain of Recombinant Human GSE1 Protein is responsible for its unique structure and function. It contains a conserved motif that plays a crucial role in protein-protein interactions, making it a potential target for drug development.

Activity of Recombinant Human GSE1 Protein

Recombinant Human GSE1 Protein has been shown to have diverse activities, making it a versatile protein in various cellular processes. It has been primarily studied for its role in DNA repair and cell cycle regulation. The protein has been found to interact with several other proteins involved in these processes, indicating its crucial role in maintaining genomic stability and cell proliferation.

Moreover, Recombinant Human GSE1 Protein has also been shown to have antioxidant activity, protecting cells from oxidative stress. This activity is attributed to its ability to scavenge free radicals and regulate cellular redox balance.

Additionally, recent studies have revealed that Recombinant Human GSE1 Protein plays a role in neuroprotection and has potential anti-inflammatory properties. It has been shown to protect neurons from oxidative stress and reduce inflammation in animal models, making it a promising candidate for the treatment of neurodegenerative diseases.

Application of Recombinant Human GSE1 Protein

Due to its diverse activities, Recombinant Human GSE1 Protein has a wide range of potential applications in various fields of research and biotechnology. One of the primary applications of this protein is in drug development. Its unique structure and essential role in cellular processes make it a potential target for drug design and discovery.

Moreover, Recombinant Human GSE1 Protein has also been used in diagnostic assays for various diseases. Its ability to interact with other proteins involved in DNA repair and cell cycle regulation makes it a potential biomarker for cancer and other genetic disorders.

Furthermore, the antioxidant and anti-inflammatory properties of Recombinant Human GSE1 Protein make it a potential therapeutic agent for various diseases. Its neuroprotective activity, in particular, has sparked interest in its potential use in the treatment of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

Conclusion

In conclusion, Recombinant Human GSE1 Protein is a unique and versatile protein with a compact structure and diverse activities. Its role in DNA repair, cell cycle regulation, and neuroprotection, along with its potential applications in drug development and diagnostics, make it a promising candidate for further research and development. With ongoing studies and advancements in recombinant protein technology, Recombinant Human GSE1 Protein holds great potential for future therapeutic and biotechnological applications.

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