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100ug, 1MG
IgG4, kappa
ProteoGenix
Primary Antibodies
Monoclonal Antibody
Mammalian cells
Elisa, WB
Dupilumab is a human monoclonal antibody of isotype IgG4 that targets the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. Dupilumab inhibits the signaling pathway of interleukins, that induce inflammatory and immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and rhinosinusitis.Dupilumab has been marketed under the trade name Dupixent. It has been also investigated for the treatment of diseases driven by allergic reactions or type 2 inflammation, such as pediatric atopic dermatitis, eosinophilic esophagitis, and chronic obstructive pulmonary disease.
Dupilumab Biosimilar - Anti-IL4R, CD124 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.
Immobilized Interleukin-4 receptor subunit alpha(IL4R) (cat. No.PX-P4860) at 0.5µg/mL (100µL/well) can bind to Dupilumab Biosimilar - Anti-IL4R, CD124 mAb (cat. No.PX-TA1308) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450
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