Skip to main content

Get 25% off your first bioreagent online order — use code: PROTEOSHOP25

Co-inhibitory & Co-stimulatory receptors

Validated Reagents for Reliable Immune Checkpoint Research

Explore our validated range of primary antibodies, research-grade biosimilars and VHH antibodies targeting key co-inhibitory and co-stimulatory receptors, with products ready to ship.

Save 20% on this selection. Use code ONCO20. Valid until September 15

180 products
  • SDS-PAGE for Abazistobart Biosimilar - Research Grade

    Abazistobart Biosimilar - Research Grade

    • PX-TA2424
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG4, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Alcestobart Biosimilar - Research Grade

    Alcestobart Biosimilar - Research Grade

    • PX-TA2373
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG4, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Abatacept Antibody (SAA2444)

    Anti-Abatacept Antibody (SAA2444)

    • PTX27090
    Clonality:
    Polyclonal Antibody
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • Anti-CD152/CTLA4 Polyclonal antibody binds to Mouse CD152 recombinant protein in WB Assay

    Anti-CD152/CTLA4 Polyclonal antibody

    • ARO-A14103
    • Validated WB
    Clonality:
    Polyclonal Antibody
    Host species:
    Rabbit
    Isotype:
    IgG
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • Anti-CD152/CTLA4 Polyclonal Antibody

    Anti-CD152/CTLA4 Polyclonal Antibody

    • ARO-A22096
    Clonality:
    Polyclonal Antibody
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Dog CD152/CTLA4 Antibody (SAA0845)

    Anti-Dog CD152/CTLA4 Antibody (SAA0845)

    • ARO-A15442
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • Anti-Human CD152/CTLA4 VHH (SAA0918)

    Anti-Human CD152/CTLA4 VHH (SAA0918)

    • PTX18946
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Human CD152/CTLA4 VHH (SAA1054)

    Anti-Human CD152/CTLA4 VHH (SAA1054)

    • PTX18947
    • Validated ELISA
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Human CD152/CTLA4 VHH (SAA1104)

    Anti-Human CD152/CTLA4 VHH (SAA1104)

    • PTX18945
    • Validated ELISA
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Human CD274/PD-L1/B7-H1 Antibody (22C3)

    Anti-Human CD274/PD-L1/B7-H1 Antibody (22C3)

    • PTX27041
    Clonality:
    Monoclonal Antibody
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • Anti-Human CD274/PD-L1/B7-H1 VHH (SAA0904)

    Anti-Human CD274/PD-L1/B7-H1 VHH (SAA0904)

    • PTX18989
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • Anti-Human CD274/PD-L1/B7-H1 VHH (SAA1141)

    Anti-Human CD274/PD-L1/B7-H1 VHH (SAA1141)

    • PTX18990
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • Anti-Human CD274/PD-L1/B7-H1 VHH (SAA1177)

    Anti-Human CD274/PD-L1/B7-H1 VHH (SAA1177)

    • PTX18988
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • Anti-Human CD279/PDCD1/PD1 Polyclonal Antibody binds to CD279 Recombinant Protein in WB Assay

    Anti-Human CD279/PDCD1/PD1 Polyclonal Antibody

    • PTX20284
    • Validated WB
    Clonality:
    Polyclonal Antibody
    Host species:
    Rabbit
    Isotype:
    IgG
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug

Co-inhibitory & Co-stimulatory Receptors

Researchers investigating immune regulation rely on co-inhibitory and co-stimulatory receptors to understand T cell activation, immune tolerance, cancer immunotherapy, autoimmune diseases, infectious diseases, and cell therapy development. Collectively, these molecules constitute the immune checkpoint pathways that regulate immune responses and have become central targets in immunology and immuno-oncology research.

ProteoGenix provides recombinant proteins and custom protein production services covering a broad range of immune checkpoint molecules and co-signaling receptors, supporting research from early discovery through preclinical development.

Top Products

Representative Immune Checkpoint Targets

Immune checkpoint research encompasses a broad network of co-inhibitory and co-stimulatory receptors involved in regulating immune activation and tolerance. Below is a representative selection of targets available through ProteoGenix.

Frequently studied co-inhibitory receptors

Frequently studied co-stimulatory receptors

Can’t find your target?

Not all immune checkpoint molecules are commercially available in the format required for your study. Our scientists can design and produce custom recombinant proteins, antibodies, Fc-fusion constructs, tagged proteins and engineered variants tailored to your experimental needs.

Explore Custom Protein Production

Supporting Every Stage of Immune Checkpoint Research

Whether your objective is basic immunology research or therapeutic development, selecting the appropriate recombinant protein is essential for obtaining reliable experimental results.

Our products are routinely used for applications including:

    • Receptor-ligand interaction studies
    • Antibody screening and characterization
    • ELISA development and validation
    • Surface Plasmon Resonance (SPR)
    • Bio-Layer Interferometry (BLI)
    • Cell-based functional assays
    • Flow cytometry assay development
    • Biomarker validation
    • Structural biology
    • Immunotherapy target evaluation
    • CAR-T and TCR research
    • Drug discovery programs

FAQ

Trusted Worldwide

Why Researchers Trust ProteoGenix

From validated reagents for co-signaling receptor research to custom antibody development, recombinant production and technical support, ProteoGenix helps researchers move faster from target selection to reliable experimental results.

  • Scientific & Technical Support

    Get expert support for product selection, format comparison, application fit and troubleshooting.

  • Quality Assurance

    Work with documented reagents supported by QC processes and batch-specific information.

  • Custom Solutions

    For specific targets or formats, ProteoGenix supports antibody development and recombinant production.

  • Global Delivery

    Reliable cold-chain logistics worldwide with temperature-controlled shipping and tracking.

Business people shaking hands in the office. Group of business persons in business meeting. Two entrepreneurs on meeting in board room. Corporate business team on meeting in modern office. Female manager discussing new project with her colleagues. Company owner on a meeting with her employee in her office.

Need a quote or more information? Contact us!

    Cart (0 Items)

    Your cart is currently empty.

    View Products