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Brand: Exbio

Anti-Hu CD24 Alexa Fluor® 700

$269.00

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Anti-Hu CD24 Alexa Fluor® 700

Anti-Hu CD24 Alexa Fluor® 700

Product name Anti-Hu CD24 Alexa Fluor® 700
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Brand ExBio
Host species Mouse
Isotype IgG1, kappa
Clonality Monoclonal Antibody
Immunogen Glycoproteins purified from human NALM-1 cell line
Clone Name SN3
Protein Name CD24
Format Liquid in stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

The mouse monoclonal antibody 581 reacts with an extracellular epitope of CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. The antibody recognizes the class III CD34 epitope resistant to neuraminidase, chymopapain and glycoprotease.

CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.

Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

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