CD160 antigen(1-158)

Reference:
Product nameCD160 antigen(1-158)
Uniprot IDO95971
Uniprot linkhttps://www.uniprot.org/uniprot/O95971
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
SequenceMLLEPGRGCCALAILLAIVDIQSGGCINITSSASQEGTRLNLICTVWHKKEEAEGFVVFLCKDRSGDCSPETSLKQLRLKRDPGIDGVGEISSQLMFTISQVTPLHSGTYQCCARSQKSGIRLQGHFFSILFTETGNYTVTGLKQRQHLEFSHNEGTLSSGFLQEKVWVMLVTSLVALQGMSKRAVSTPSNEGAGGGSGGHHHHHHHH
Molecular weight22.52kDa
Purity estimated>70% by SDS-PAGE
BufferPBS, pH=7.5
Delivery conditionDry Ice
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesMammalian cells
ApplicationsELISA,WB
Fragment TypeMet1-Leu158
Aliases /SynonymsNatural killer cell receptor BY55,CD_antigen: CD160,BY55,CD160-TM
ReferencePX-P4287
NoteFor research use only.

Description of CD160 antigen(1-158)

General information on CD160 antigen (CD160):

The CD160 antigen is a protein encoded by the CD160 gene in humans. CD160 is a glycoprotein that was originally identified with the monoclonal antibody BY55. Its expression is strictly related to peripheral blood NK cells and cytolytically active CD8 T lymphocytes. The CD160 cDNA sequence can be predicted to be rich in 18-colored glycosylphosphatidylinositol amino acids, with a single Ig-like domain that is weakly homologous to the KIR2DL4 molecule. CD160 is expressed on the cell surface as a multimer with tightly bound disulfide bonds. Northern blot analysis showed that the CD160 mRNA was 1.5 and 1.6 kb, and its expression was very limited to circulating NK and T cells, spleen, and small intestine. In NK cells, CD160 is expressed by CD56dimCD16 + cells, while in circulating T cells, its expression is mainly limited to cells carrying TCRgd and TCRab + CD8brightCD95 + CD56 + CD28-CD27-CD27 cells. In tissue, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 exhibits broad specificity for the binding of classical and unconventional MHC class I molecules.

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