Pembrolizumab Biosimilar – Anti-PD1 mAb – Research Grade

Reference:
Size

,

Isotype

IgG4

Brand

Product type

Clonality

Expression system

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Product namePembrolizumab Biosimilar - Anti-PD1 mAb - Research Grade
SourceDrugBank DB09037
SpeciesHuman
Molecular weight149kDa
Purity>85%
BufferPBS pH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /SynonymsPembrolizumab,Pembrolizumab,PD1,anti-PD1
ReferencePX-TA1007
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG4
ClonalityMonoclonal Antibody

Description of Pembrolizumab Biosimilar - Anti-PD1 mAb - Research Grade

General information about Pembrolizumab

Pembrolizumab is a humanized antibody used in cancer immunotherapy. This includes to treat melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, and stomach cancer. It is given by slow injection into a vein. It is an IgG4 isotype antibody that blocks a protective mechanism of cancer cells and thereby, allows the immune system to destroy them. It targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes. It works by targeting the cellular pathway of proteins found on the body’s immune cells and some cancer cells, known as PD-1/PD-L1. This product is for research use only.

SDS-PAGE for Pembrolizumab Biosimilar - Anti-PD1 mAb

Pembrolizumab Biosimilar - Anti-PD1 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

Pembrolizumab Biosimilar - Anti-PD1 mAb binds to CD279 Recombinant Protein in indirect ELISA Assay

Immobilized CD279 Recombinant Protein (cat. No.PX-P4117) at 0.5µg/mL (100µL/well) can bind to Pembrolizumab Biosimilar - Anti-PD1 mAb (cat. No.PX-TA1007) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

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