Satralizumab Biosimilar – Anti-IL6R mAb – Research Grade

Reference:
Size

,

Isotype

IgG2, kappa

Brand

Product type

Clonality

Expression system

Applications

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Product nameSatralizumab Biosimilar - Anti-IL6R mAb - Research Grade
SourceCAS 1535963-91-7
SpeciesHumanized
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsSatralizumab,SA-237,IL6R,anti-IL6R
ReferencePX-TA1407
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG2-kappa
ClonalityMonoclonal Antibody

Description of Satralizumab Biosimilar - Anti-IL6R mAb - Research Grade

General information on Anti-IL6R[Homo sapiens] (Satralizumab) Monoclonal Antibody

Satralizumab is a humanized monoclonal antibody that targets human interleukin-6 (IL-6) receptors, similar to tocilizumab. Satralizumab is used to treat neuromyelitis optica spectrum disorder (NMOSD). Increased production of anti-aquaporin-4 (AQP4) autoantibodies and increased permeability of the blood-brain barrier are thought to be mediated by IL-6. Satralizumab is thought to block IL-6 receptors and, thereby, these inflammatory responses.

Satralizumab Biosimilar - Anti-IL6R mAb binds to CD126 Recombinant Protein in indirect ELISA Assay

Immobilized CD126 Recombinant Protein (cat. No.PX-P4104) at 0.5µg/mL (100µL/well) can bind to Satralizumab Biosimilar - Anti-IL6R mAb (cat. No.PX-TA1407) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

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