Interleukin-1 alpha(IL1A)

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100ug, 50ug

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Product nameInterleukin-1 alpha(IL1A)
Uniprot IDP01583
Uniprot linkhttp://www.uniprot.org/uniprot/P01583
Expression systemProkaryotic expression
SequenceSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA
Molecular weight19.2kDa
Purity estimated>90% by SDS-PAGE
Buffer50 mM Tris-HCl pH 8.0, 150 mM NaCl
Delivery conditionDry Ice
Delivery lead time in business daysEurope: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
ApplicationsELISA,WB
Fragment TypeSer113-Ala271
Aliases /SynonymsIL1F1,Hematopoietin-1
ReferencePX-P4588
NoteFor research use only

Description of Interleukin-1 alpha(IL1A)

General Information about Interleukin-1 alpha (IL1)

The protein encoded by this gene is a member of the interleukin-1 cytokine family. This cytokine is a pleiotropic cytokine involved in a variety of immune responses, inflammatory processes and hematopoiesis. The cytokine is produced by monocytes and macrophages in the form of proprotein, which is proteolytically processed and released in response to cell damage, thereby inducing apoptosis. This gene and 8 other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been shown that these gene polymorphisms are related to rheumatoid arthritis and Alzheimer’s disease.

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