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Brand: ProteoGenix

Microtubule-associated protein tau(MAPT)(1-441)

Host species:
Escherichia coli (E.coli)
Uniprot ID:
P10636-8

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Met1–Leu441
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Microtubule-associated protein tau(MAPT)(1-441)

Product name Microtubule-associated protein tau(MAPT)(1-441)
Uniprot ID P10636-8
Uniprot link http://www.uniprot.org/uniprot/P10636-8
Expression system Prokaryotic expression
Sequence MGSHHHHHHSGMAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKST PTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVV RTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIV YKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Purity estimated >80% by SDS-PAGE
Buffer PBS pH7.5
Delivery condition Dry Ice
Delivery lead time in business days Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Escherichia coli (E.coli)
Fragment Type Met1-Leu441
Aliases /Synonyms Neurofibrillary tangle protein,Paired helical filament-tau,MAPTL, MTBT1, TAU
Reference PX-P4601
Note For research use only
Molecular Constructor
Met1–Leu441
Product name Microtubule-associated protein tau(MAPT)(1-441)
Uniprot ID P10636-8
Uniprot link http://www.uniprot.org/uniprot/P10636-8
Expression system Prokaryotic expression
Sequence MGSHHHHHHSGMAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKST PTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVV RTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIV YKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Purity estimated >80% by SDS-PAGE
Buffer PBS pH7.5
Delivery condition Dry Ice
Delivery lead time in business days Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Escherichia coli (E.coli)
Fragment Type Met1-Leu441
Aliases /Synonyms Neurofibrillary tangle protein,Paired helical filament-tau,MAPTL, MTBT1, TAU
Reference PX-P4601
Note For research use only
Molecular Constructor
Met1–Leu441

General Information about Microtubule-associated protein tau (MAPT)

Microtubule-associated protein tau (MAPT) promotes microtubule assembly and stability, and may participate in the establishment and maintenance of neuronal polarity. The C-terminus binds to axon microtubules, while the N-terminus binds to the plasma membrane components, indicating that tau acts as a linker between the two. Axon polarity is predetermined by the TAU/MAPT positioning (in neuronal cells) in the cell body domain defined by the centrosome. The short isoform can make the cytoskeleton plastic, while the longer isoform can give priority to its stabilizing effect.

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