Mipletamig Biosimilar – Anti-IL-3R subunit alpha;CD3e mAb – Research Grade

Reference:
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,

Brand

Isotype

Ig IG chain scFvkh-G1hCH2CH3-scFvhk dimer bisdisulfide

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Clonality

Expression system

Product nameMipletamig Biosimilar - Anti-IL-3R subunit alpha;CD3e mAb - Research Grade
SourceBispecific, Tetravalent, CAS: 2839556-21-5
Origin speciesHuman
Expression systemXtenCHO
Purity>95% by SDS-PAGE
Buffer0.01M PBS, pH 7.4
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /Synonymsanti-IL-3R subunit alpha, IL-3 receptor subunit alpha, CD123, Interleukin-3 receptor subunit alpha, IL3R, IL-3R-alpha, IL3RA, IL-3RA, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
ReferencePX-TA2200-100
NoteFor research use only. Not suitable for human use.
IsotypeIg IG chain scFvkh-G1hCH2CH3-scFvhk dimer bisdisulfide
ClonalityMonoclonal Antibody

Description of Mipletamig Biosimilar - Anti-IL-3R subunit alpha;CD3e mAb - Research Grade

Introduction

Mipletamig Biosimilar – Anti-IL-3R subunit alpha;CD3e mAb – Research Grade is a therapeutic antibody that targets the IL-3 receptor subunit alpha and the CD3e protein. This biosimilar is designed to mimic the activity of the original therapeutic antibody, Mipletamig, which is used to treat various inflammatory conditions. In this article, we will discuss the structure, activity, and potential applications of Mipletamig Biosimilar in the field of medicine.

Structure of Mipletamig Biosimilar

Mipletamig Biosimilar is a monoclonal antibody, which means it is derived from a single clone of immune cells. It is composed of two heavy chains and two light chains, connected by disulfide bonds. The heavy chains are responsible for the antibody’s binding activity, while the light chains help to stabilize the structure. The antibody has a Y-shaped structure, with two antigen-binding sites at the tips of the Y, allowing it to bind to its target with high specificity.

Activity of Mipletamig Biosimilar

Mipletamig Biosimilar is a targeted therapy that specifically binds to the IL-3 receptor subunit alpha and the CD3e protein. These proteins are found on the surface of immune cells, including T cells and mast cells, and play a crucial role in mediating inflammatory responses. By binding to these proteins, Mipletamig Biosimilar blocks their activity and reduces the production of inflammatory cytokines, ultimately leading to a decrease in inflammation.

Therapeutic Target of Mipletamig Biosimilar

The therapeutic target of Mipletamig Biosimilar is the IL-3 receptor subunit alpha and the CD3e protein. These proteins are involved in the activation and proliferation of immune cells, which can lead to excessive inflammation in various diseases. By targeting these proteins, Mipletamig Biosimilar can effectively modulate the immune response and provide relief from inflammatory conditions.

Applications of Mipletamig Biosimilar

Mipletamig Biosimilar has a wide range of potential applications in the field of medicine. It can be used to treat various inflammatory conditions, such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. It has also shown promising results in the treatment of allergic diseases, such as asthma and atopic dermatitis. Furthermore, Mipletamig Biosimilar has the potential to be used in combination with other therapies, such as chemotherapy, to enhance their effectiveness.

Research Grade Mipletamig Biosimilar

Mipletamig Biosimilar is available in a research grade, which is specifically designed for use in laboratory research. This grade of the biosimilar is highly pure and free from any contaminants, ensuring reliable and reproducible results in experiments. Researchers can use the research grade Mipletamig Biosimilar to study the mechanisms of inflammation and develop new therapeutic strategies for inflammatory diseases.

Conclusion

In summary, Mipletamig Biosimilar – Anti-IL-3R subunit alpha;CD3e mAb – Research Grade is a therapeutic antibody that targets the IL-3 receptor subunit alpha and the CD3e protein. It has a well-defined structure and a targeted mechanism of action, making it a promising therapy for various inflammatory conditions. With further research and development, Mipletamig Biosimilar has the potential to improve the lives of patients suffering from inflammatory diseases.

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