Stable Isotope Labelled Dupilumab Biosimilar – Anti-IL4R/CD124 mAb – Research Grade

Reference: PX-TA1308-SIL-1MG
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Product nameStable Isotope Labelled Dupilumab Biosimilar - Anti-IL4R/CD124 mAb - Research Grade
SourceCAS 1190264-60-8
SpeciesHomo sapiens
Expression systemMammalian cells
Purity>95%
BufferPBS buffer PH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
ApplicationsMS
Aliases /SynonymsCD124,REGN668,SAR231893
ReferencePX-TA1308-SIL
Related ProductsPX-P4881
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG4-kappa
ClonalityMonoclonal Antibody
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year

Description of Dupilumab Biosimilar - Anti-IL4R/CD124 mAb - Research Grade

General information on Anti-IL4R/CD124[Homo sapiens] (Dupilumab) Monoclonal Antibody

Dupilumab is a human monoclonal antibody of isotype IgG4 that targets the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. Dupilumab inhibits the signaling pathway of interleukins, that induce inflammatory and immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and rhinosinusitis.Dupilumab has been marketed under the trade name Dupixent. It has been also investigated for the treatment of diseases driven by allergic reactions or type 2 inflammation, such as pediatric atopic dermatitis, eosinophilic esophagitis, and chronic obstructive pulmonary disease.

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