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Brand: ProteoGenix

Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade

Clonality:
Monoclonal Antibody
Isotype:
IgG1, lambda2

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Temtokibart Biosimilar - Anti-CRF2-9 mAb - Research Grade

Product name Temtokibart Biosimilar - Anti-CRF2-9 mAb - Research Grade
Source CAS: 2639874-57-8
Species Human
Buffer 0.01M PBS, pH 7.4
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3 week if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB
Aliases /Synonyms anti-CRF2-9, IL-22RA1, IL22RA1, ZcytoR11, IL-22R-alpha-1, IL-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, Interleukin-22 receptor subunit alpha-1, Cytokine receptor family 2 member 9, IL22R
Reference PX-TA1973
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-lambda2
Clonality Monoclonal Antibody
Product name Temtokibart Biosimilar - Anti-CRF2-9 mAb - Research Grade
Source CAS: 2639874-57-8
Species Human
Buffer 0.01M PBS, pH 7.4
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3 week if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB,,,
Aliases /Synonyms anti-CRF2-9, IL-22RA1, IL22RA1, ZcytoR11, IL-22R-alpha-1, IL-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, Interleukin-22 receptor subunit alpha-1, Cytokine receptor family 2 member 9, IL22R
Reference PX-TA1973
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-lambda2
Clonality Monoclonal Antibody

Introduction:

Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade is a novel biosimilar antibody that has been developed to target the corticotropin-releasing factor receptor 2 (CRF2-9). This antibody has been designed to mimic the activity of the naturally occurring antibody and has shown promising results in pre-clinical studies. In this article, we will discuss the structure, activity, and potential applications of Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade.

Structure of Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade:

Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade is a monoclonal antibody, meaning it is produced by a single clone of cells. It is a recombinant antibody, which means it is produced in a laboratory using genetic engineering techniques. The antibody is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains are approximately 150 kDa in size, while the light chains are around 25 kDa. The antibody also contains a variable region that is responsible for binding to the CRF2-9 receptor.

Activity of Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade:

The main activity of Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade is to bind to the CRF2-9 receptor. This receptor is found on the surface of certain cells in the brain and is involved in the regulation of stress and anxiety. By binding to the receptor, the antibody can block the activity of CRF2-9, which can lead to a decrease in stress and anxiety levels. In pre-clinical studies, Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade has been shown to reduce stress-related behaviors in animal models.

Potential Applications of Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade:

Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade has the potential to be used as a therapeutic agent for a variety of conditions related to stress and anxiety. It may also have applications in the treatment of certain psychiatric disorders, such as depression and post-traumatic stress disorder (PTSD). Additionally, the antibody may have potential in the management of chronic pain and inflammatory conditions, as CRF2-9 has been shown to play a role in these processes.

Mechanism of Action:

The mechanism of action of Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade is through the binding and inhibition of CRF2-9. By blocking the activity of this receptor, the antibody can modulate the stress response and reduce anxiety-related behaviors. It is also believed that the antibody may have a neuroprotective effect, as CRF2-9 has been linked to neuronal damage and degeneration.

Future Directions:

Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade is currently in pre-clinical development and has not yet been approved for human use. However, the promising results from animal studies suggest that this antibody may have potential as a therapeutic agent for stress and anxiety-related disorders. Further research and clinical trials are needed to evaluate the safety and efficacy of this biosimilar antibody.

Conclusion:

In conclusion, Temtokibart Biosimilar – Anti-CRF2-9 mAb – Research Grade is a novel biosimilar antibody that has been designed to target the CRF2-9 receptor. Its structure, activity, and potential applications make it a promising candidate for the treatment of stress and anxiety-related disorders. Further research and development of this antibody may lead to a new therapeutic option for patients suffering from these conditions.

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