CD126 Recombinant Protein

Reference: PX-P4104-100
Size

100ug

Brand

Product type

Host Species

Applications

,

Product nameCD126 Recombinant Protein
Uniprot IDP08887
Uniprot linkhttp://www.uniprot.org/uniprot/P08887
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
SequenceMLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSSSVPLP
Molecular weight65kDa
Protein delivered with Tag?C-terminal His Tag
Purity estimated>90% by SDS-PAGE
BufferPBS pH7.5
Delivery conditionDry Ice
Storage conditionStore at - 20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage.
BrandProteoGenix
Host speciesMammalian cells
ApplicationsELISA,WB
Fragment TypeMet1~Pro365
Aliases /Synonyms/
ReferencePX-P4104
NoteFor research use only

Description of CD126 Recombinant Protein

General Information about CD126 Recombinant Protein

The interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor.
Interleukin 6 (IL6) is an effective pleiotropic cytokine that can regulate cell differentiation and differentiation and plays an important role in the immune response. The unregulated production of IL6 and this receptor is involved in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
In melanocytes, IL6R gene expression can be regulated by MITF. The IL6 receptor is a protein complex composed of the ILUN-6 receptor subunit (IL6R) and the signal transduction glycoprotein 130 of interleukin 6. IL6R is also known as the human gene encoding this subunit. It is possible to report alternative transcription variants that encode different isoforms. The IL6R subunit is also shared by many other cytokines.

Sarilumab Biosimilar - Anti-IL-6R mAb binds to CD126 Recombinant Protein in indirect ELISA Assay

Immobilized CD126 Recombinant Protein (cat. No.PX-P4104) at 0.5µg/mL (100µL/well) can bind to Sarilumab Biosimilar - Anti-IL-6R mAb (cat. No.PX-TA1028) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

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