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Brand: ProteoGenix

Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)

Clonality:
Monoclonal Antibody

Original price was: $333.00.Current price is: $275.00.

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Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)

Product name ARO-A23271-100
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Aliases /Synonyms Anti-Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2
Clonality Monoclonal Antibody
Protein Name Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2
Product name ARO-A23271-1MG
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Aliases /Synonyms Anti-Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2
Clonality Monoclonal Antibody
Protein Name Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2
Product name ARO-A23271-50
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Aliases /Synonyms Anti-Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2
Clonality Monoclonal Antibody
Protein Name Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2

Introduction

Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) is a powerful tool used in various research and diagnostic applications. This monoclonal antibody specifically targets the CD23 protein, also known as the Fc epsilon receptor II (FCER2), which is found on the surface of certain immune cells. In this article, we will discuss the structure, activity, and applications of Anti-Human CD23/FCER2 Monoclonal Antibody (1A503).

Structure of Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)

Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) is a type of monoclonal antibody, meaning it is produced from a single clone of cells. This ensures that each antibody is identical and specific to its target, in this case, the CD23 protein. The antibody is composed of two heavy chains and two light chains, connected by disulfide bonds. The variable regions of the antibody, which bind to the CD23 protein, are located at the tips of the “Y” shape.

Activity of Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)

Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) works by binding to the CD23 protein on the surface of immune cells, specifically B cells and macrophages. This binding triggers a series of events that can modulate the activity of these cells. For example, CD23 is known to play a role in the regulation of IgE production, and by binding to CD23, Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) can block this process.

In addition, CD23 is also involved in the activation and differentiation of B cells. By targeting CD23, Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) can affect the function of these cells, potentially leading to changes in the immune response.

Applications of Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)

Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) has a wide range of applications in both research and diagnostics. Some of the key applications include:

1. Immunohistochemistry (IHC)

Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) can be used in IHC to detect the presence and distribution of CD23 in tissue samples. This is particularly useful in identifying B cell lymphomas, as CD23 is highly expressed in these types of cancers.

2. Flow Cytometry

Flow cytometry is a powerful technique used to analyze and sort cells based on their surface markers. Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) can be used in flow cytometry to identify and isolate CD23-expressing cells, providing valuable information about the immune cell population.

3. Neutralization Assays

As mentioned earlier, Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) can block the activity of CD23. This property makes it useful in neutralization assays, where the antibody can be used to inhibit the function of CD23 and study its role in various biological processes.

4. Drug Development

CD23 has been identified as a potential therapeutic target in various diseases, including asthma and autoimmune disorders. Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) can be used in drug development to study the role of CD23 and evaluate the efficacy of potential treatments.

Conclusion

In summary, Anti-Human CD23/FCER2 Monoclonal Antibody (1A

SDS-PAGE for Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)

SDS-PAGE for Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)

Anti-Human CD23/FCER2 Monoclonal Antibody (1A503), on SDS-PAGE. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

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