Antibody-drug conjugates
-
Antibody-drug conjugatesHow to choose the best linker for an ADC? Cleavable vs. non-cleavable
Ana Reis, PhD
Antibody-drug conjugate linker chemistry has greatly evolved since the development of the first molecules. Linkers can be defined as the interface between chemistry and biology. For this reason, they…
-
How to select the right antibody carrier for ADCs?
Monoclonal antibodies are essential precursors of ADCs. Choosing the proper antibody for the conjugate often dictates its therapeutic efficiency. Several… Read More
-
How are antibodies conjugated?
Antibody-drug conjugates (ADC) are one of the fastest-growing classes of biopharmaceuticals. The conjugation between the antibody carrier of… Read More
-
Antibody-drug conjugates: Antibody design and conjugation
The careful design and engineering of monoclonal antibody carriers should precede any effort in ADC generation. Target selection and… Read More
