Stable Isotope Labelled Alirocumab Biosimilar – Anti-PCSK9 mAb – Research Grade

Reference: PX-TA1287-SIL-1MG
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Product nameStable Isotope Labelled Alirocumab Biosimilar - Anti-PCSK9 mAb - Research Grade
SourceCAS 1245916-14-6
SpeciesHomo sapiens
Expression systemMammalian cells
Molecular weight146kDa
Purity>95%
BufferPBS buffer PH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
ApplicationsMS
Aliases /SynonymsREGN727,SAR-236553
ReferencePX-TA1287-SIL
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1-kappa
ClonalityMonoclonal Antibody
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year

General information on Anti-PCSK9[Homo sapiens] (Alirocumab) Monoclonal Antibody

Alirocumab is a human IgG2 monoclonal antibody that binds to and prevents the binding of the proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a protein that binds to LDL receptors for degradation, thus reducing the liver’s activity of removal of LDL-cholesterol (LDL-C) from the blood. It is used in the treatment of hyperlipidemia.

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