Stable Isotope Labelled Ipilimumab Biosimilar – Anti-CTLA-4 mAb – Research Grade

Reference: PX-TA1021-SIL-1MG
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Expression system

Applications

Product nameStable Isotope Labelled Ipilimumab Biosimilar - Anti-CTLA-4 mAb - Research Grade
SourceDrugBank DB06186
SpeciesHuman
Expression systemMammalian cells
Molecular weight148kDa
Purity>95%
BufferPBS pH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
ApplicationsMS
Aliases /SynonymsIpilimumab
ReferencePX-TA1021-SIL
Related ProductsPX-P4782
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1Kappa
ClonalityMonoclonal Antibody
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year
FormulaC6572H10126N1734O2080S40

General information about Ipilimumab

Ipilimumab is a monoclonal antibody used in the treatment of melanoma. It is an antibody that inhibits the CTLA-4 checkpoint of T lymphocytes, a checkpoint that certain cancers activate to decrease the efficiency of the lymphocyte. Ipilimumab is a human monoclonal antibody of the IgG1 type directed against the CTLA-4 protein (Cytotoxic T-Lymphocyte Antigen 4). The inhibition of this receptor present on the T lymphocytes results in the activation of the T lymphocyte. This product is for research use only.

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