Brand: ProteoGenix

Modotuximab Biosimilar – Anti-EGFR, ERBB1 domain III mAb – Research Grade

PX-TA1305-100UG
Validated ELISA FC

Clonality:: Monoclonal Antibody
Isotype:: IgG1, kappa

Original price was: $300.00.Current price is: $238.00.

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50ug Original price was: $209.00.Current price is: $167.00.
100ug Original price was: $300.00.Current price is: $238.00.
1MG Original price was: $670.00.Current price is: $482.00.

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Modotuximab Biosimilar - Anti-EGFR, ERBB1 domain III mAb binds to Human EGFR/ERBB1/HER1 in indirect ELISA Assay

Flow Cytometry results for Modotuximab Biosimilar - Anti-EGFR;ERBB1 mAb - Research Grade

37 clones available

Modotuximab Biosimilar - Anti-EGFR, ERBB1 domain III mAb - Research Grade

Product name	Modotuximab Biosimilar - Anti-EGFR, ERBB1 domain III mAb - Research Grade
Uniprot ID	P00533
Source	CAS 1310460-86-6
Species	Chimeric
Raw Antigen Sequence	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA
Purity	>85%
Buffer	PBS buffer PH7.5
Delivery condition	Blue ice (+4°C)
Delivery Time	3-5 days if in stock; 3-5 weeks if production needed
Storage condition	store at -80°C
Brand	ProteoGenix
Applications	ELISA,WB
Aliases /Synonyms	Modotuximab,DS 1024,Sym 004 (combination of modotuximab and futuximab),EGFR, ERBB1 domain III,anti-EGFR, ERBB1 domain III
Reference	PX-TA1305
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype	IgG1-kappa
Clonality	Monoclonal Antibody

Product name	Modotuximab Biosimilar - Anti-EGFR, ERBB1 domain III mAb - Research Grade
Uniprot ID	P00533
Source	CAS 1310460-86-6
Species	Chimeric
Raw Antigen Sequence	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA
Purity	>85%
Buffer	PBS buffer PH7.5
Delivery condition	Blue ice (+4°C)
Delivery Time	3-5 days if in stock; 3-5 weeks if production needed
Storage condition	store at -80°C
Brand	ProteoGenix
Applications	ELISA,WB,,,
Aliases /Synonyms	Modotuximab,DS 1024,Sym 004 (combination of modotuximab and futuximab),EGFR, ERBB1 domain III,anti-EGFR, ERBB1 domain III
Reference	PX-TA1305
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype	IgG1-kappa
Clonality	Monoclonal Antibody

Product name	PX-TA1305-50
Uniprot ID	P00533
Source	CAS 1310460-86-6
Species	Chimeric
Raw Antigen Sequence	MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA
Purity	>85%
Buffer	PBS buffer PH7.5
Delivery condition	Blue ice (+4°C)
Delivery Time	3-5 days if in stock; 3-5 weeks if production needed
Storage condition	store at -80°C
Brand	ProteoGenix
Aliases /Synonyms	Modotuximab,DS 1024,Sym 004 (combination of modotuximab and futuximab),EGFR, ERBB1 domain III,anti-EGFR, ERBB1 domain III
Reference	PX-TA1305
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype	IgG1, kappa
Clonality	Monoclonal Antibody

General information on Anti-EGFR/ERBB1 domain III[Homo sapiens] (Modotuximab) Monoclonal Antibody

Modotuximab is investigated for the treatment of metastatic Colorectal Cancer (mCRC).

Modotuximab Biosimilar - Anti-EGFR, ERBB1 domain III mAb binds to Human EGFR/ERBB1/HER1 in indirect ELISA Assay

Immobilized EGFR / ERBB1 / HER1, C-His, recombinant protein (cat. No.PX-P5701) at 0.5µg/mL (100µL/well) can bind Modotuximab Biosimilar - Anti-EGFR, ERBB1 domain III mAb (cat. No.PX-TA1305) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 0.5282M.

Flow Cytometry results for Modotuximab Biosimilar - Anti-EGFR;ERBB1 mAb - Research Grade

Target Cells were stained with an irrelevant antibody or Modotuximab Biosimilar - Anti-EGFR;ERBB1 mAb - Research Grade at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG Polyclonal Antibody, FITC (PTX18862) and cells analysed on a NovoCyte Flow Cytometer.

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Name	SKU	View Clone
Anti-Human EGFR/ERBB1/HER1 VHH (SAA1207)	PTX18907-100	View Clone
Anti-Human EGFR/ERBB1/HER1 VHH (SAA0906)	PTX18905-100	View Clone
Anti-Human EGFR/ERBB1/HER1 Human Antibody (11F8), APC	ARO-A10438	View Clone
Anti-Human EGFR/ERBB1/HER1 Antibody (E7.6.3), APC	ARO-A10437	View Clone
Anti-Human EGFR/ERBB1/HER1 Antibody (E7.6.3), FITC	ARO-A10941	View Clone
Anti-Human EGFR/ERBB1/HER1 Mouse Antibody (11F8), FITC	ARO-A10940	View Clone
Anti-Human EGFR/ERBB1/HER1 VHH (SAA1292)	PTX18909-100	View Clone
Anti-Human EGFR/ERBB1/HER1 Mouse Antibody (11F8), APC	ARO-A10436	View Clone
Modotuximab Biosimilar - Anti-EGFR, ERBB1 domain III mAb - Research Grade	PX-TA1305	View Clone
Tomuzotuximab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1473	View Clone
Depatuxizumab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1435	View Clone
Demupitamab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1655	View Clone
Futuximab Biosimilar - Anti-EGFR domain III , ERBB1 mAb - Research Grade	PX-TA1293	View Clone
Imgatuzumab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1294	View Clone
Laprituximab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1418	View Clone
Losatuxizumab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1457	View Clone
Nimotuzumab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1054	View Clone
Serclutamab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1553	View Clone
Zalutumumab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1151	View Clone
Pimurutamab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1703	View Clone
Panitumumab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1148	View Clone
Necitumumab Biosimilar - Anti-EGFR, ERBB1 mAb - Research Grade	PX-TA1209	View Clone
Bafisontamab Biosimilar - Anti-ERBB1 mAb - Research Grade	PX-TA1791	View Clone
Becotatug Biosimilar - Anti-HER1 mAb - Research Grade	PX-TA2048	View Clone
Matuzumab Biosimilar - Anti-EGFR mAb - Research Grade	PX-TA1041	View Clone
Cetuximab Biosimilar - Anti-hEGFR mAb - Research Grade	PX-TA1019	View Clone
Human EGFR/ERBB1/HER1 (E7.6.3) Monoclonal Antibody	ARO-A16066	View Clone
Human EGFR/ERBB1/HER1 Monoclonal Antibody	ARO-A16069	View Clone
Anti-Human EGFR/ERBB1/HER1 Antibody (11F8), FITC	ARO-A10942	View Clone
Anti-Human EGFR/ERBB1/HER1 Human Antibody (11F8), PerCP	ARO-A10187	View Clone
Anti-Human EGFR/ERBB1/HER1 Mouse Antibody (11F8), PerCP	ARO-A10185	View Clone
Anti-Human EGFR/ERBB1/HER1 Human Antibody (11F8), PE	ARO-A10703	View Clone
Anti-Human EGFR/ERBB1/HER1 Antibody (E7.6.3), PE	ARO-A10702	View Clone
Anti-Human EGFR/ERBB1/HER1 Antibody (11F8), PE	ARO-A10701	View Clone
Anti-Human EGFR/ERBB1/HER1 VHH (SAA0792)	PTX18892-100	View Clone
Anti-Human EGFR/ERBB1/HER1 VHH (SAA1038)	PTX18906-100	View Clone
Anti-Human EGFR/ERBB1/HER1 VHH (SAA1213)	PTX18908-100	View Clone